Reverse Osmosis Membrane Model TML20N-400 Applied In Pharmaceutical Water

Introduction

The TML20N-400 reverse osmosis (RO) membrane, part of the Toray membrane series, is engineered to deliver high-performance water purification across industrial and municipal applications. Manufactured with cutting-edge composite polyamide technology, this membrane excels in removing dissolved salts, organic contaminants, and microorganisms, ensuring compliance with stringent water quality standards. Designed for brackish water and high-efficiency desalination, the TML20N-400 is ideal for pharmaceutical water production, wastewater reuse, and other critical processes requiring ultra-pure water.

Technical Specifications

The TML20N-400 combines robust construction with optimized operational parameters, as detailed below:

*Test conditions: 2,000 ppm NaCl solution, 225 psi (1.55 MPa), 77°F (25°C), pH 7.5, 15% recovery.

Working Principle

The TML20N-400 operates on the principle of reverse osmosis, leveraging semi-permeable membrane technology to separate impurities from water. Here’s how it works:

1. Pressure Application: Feedwater is pressurized to overcome osmotic pressure, forcing water molecules through the membrane’s dense polymer layer.

2. Selective Filtration: The membrane’s ultra-thin polyamide layer rejects dissolved ions (e.g., Na⁺, Cl⁻), organics, and particles >0.0001 microns, while allowing pure water to permeate.

3. Crossflow Design: A portion of the feedwater (concentrate) flows tangentially across the membrane surface, sweeping away contaminants and minimizing fouling.

This process achieves up to 99.8% salt rejection, making it suitable for high-purity applications.

Performance & Advantages

The TML20N-400 stands out for its exceptional efficiency and durability:

Key Advantages

• High Salt Rejection: Consistently achieves >99.5% NaCl rejection, ensuring ultra-pure permeate.

• Low Energy Consumption: Operates efficiently at moderate pressures (200–600 psi), reducing operational costs.

• Fouling Resistance: Hydrophilic membrane surface minimizes adhesion of colloids and organics.

• Chemical Stability: Tolerates wide pH ranges and aggressive cleaning agents (e.g., citric acid, NaOH).

• Long Service Life: Robust glass fiber-reinforced outer layer withstands mechanical stress and pressure fluctuations.

Performance Metrics

Product Structure

The TML20N-400 features a spiral-wound design optimized for durability and flow dynamics:

1. Membrane Leaves: Multiple layers of polyamide active film and polysulfone support, rolled around a perforated central tube.

2. Feed Spacer: 34-mil thickness to enhance turbulence and reduce fouling.

3. Permeate Channel: Multi-layered porous substrate for low-resistance water collection.

4. Fiberglass Shell: Protects against abrasion and maintains structural integrity under high pressure.

Application in Pharmaceutical Water

Pharmaceutical-grade water demands zero compromises in purity. The TML20N-400 is integral to producing Water for Injection (WFI) and Purified Water (PW) systems:

• Contaminant Removal: Eliminates endotoxins, pyrogens, and ionic impurities to meet USP/EP standards.

• Consistency: Stable performance under variable feed conditions (TDS <5,000 ppm).

• Validation Support: Compatible with CIP/SIP protocols, ensuring compliance with GMP requirements.

Case Study: A leading pharmaceutical plant in Europe achieved a 30% reduction in downtime after switching to TML20N-400 membranes, with permeate conductivity consistently <5 μS/cm.

Other Applications

Beyond pharmaceuticals, the TML20N-400 serves diverse sectors:

1. Food & Beverage: Desalination of process water, syrup concentration, and wastewater recovery.

2. Power Generation: Boiler feedwater treatment and cooling tower blowdown recycling.

3. Municipal Water: Seawater desalination and brackish water treatment for potable supply.

4. Electronics: Ultra-pure water production for semiconductor manufacturing.

Conclusion

The Toray TML20N-400 reverse osmosis membrane sets a benchmark in reliability and efficiency for high-stakes water treatment. With its superior salt rejection, fouling resistance, and adaptability across industries, it is the optimal choice for applications demanding uncompromised water quality. Partnering with XINXIANG LIFEIERTE FILTER CORP., LTD ensures access to technical expertise and global support, empowering industries to achieve sustainability and operational excellence.

Common Part Numbers